{"procedure":{"id":"aesthefill","name":"艾塑菲（AestheFill）","type":"individual","family":"聚消旋乳酸（PDLLA）胶原蛋白再生剂","category":"聚消旋乳酸（PDLLA）胶原蛋白再生剂","price":"high","pain":2,"downtime":2,"visible_in":1,"lasts":4,"summary":"PDLLA胶原蛋白刺激剂","explanation":"Aesthefill是一种PDLLA胶原蛋白刺激类注射剂，用于循序渐进地支撑容量并提升皮肤紧致度。最适合追求以胶原蛋白为主导的年轻化、而非即刻玻尿酸填充效果的人群。","target":"面部饱满度、肌肤紧致","description":"Aesthefill是一种PDLLA胶原蛋白刺激类注射剂，用于循序渐进地支撑容量并提升皮肤紧致度。最适合追求以胶原蛋白为主导的年轻化、而非即刻玻尿酸填充效果的人群。","detail":{"id":"aesthefill","name":"Aesthefill","price":{"basis":"1 vial (200 mg) per session (estimate)","krw_max":900000,"krw_min":400000,"varies_by":"vial"},"dosage":{"unit":"vial","options":[{"tag":"Standard","note":"Standard single session","amount":"1 vial","coverage":"Full face or one larger area","description":"Commonly used for a full-face or temple/cheek session.","krw_typical":600000},{"tag":"Series","note":"Spaced 4-6 weeks apart","amount":"1 vial × 2-3 sessions","coverage":"Full face series","description":"A short series gives a more noticeable, longer-lasting collagen effect.","krw_typical":1600000}],"unit_explainer":"One vial = 200 mg of freeze-dried PDLLA powder, diluted before injection. Dose is set by area size; a series of sessions builds collagen gradually."},"header":{"one_liner":"PDLLA collagen stimulator that rebuilds volume and firmness gradually over months.","target_tags":["Volume loss","Firmness","Temples","Cheeks","Skin quality"],"category_label":"REGENERATION","technology_label":"PDLLA"},"details":{"sessions":"Usually 2-3 sessions","aftercare":"Massage as instructed (often several times daily for ~5 days); avoid heat and intense exercise for a few days; results build slowly — wait for collagen to form before judging.","anesthesia":"Numbing cream; lidocaine often added to the suspension","regulatory":"MFDS approved (Korea); approved in several markets incl. Brazil (expert consensus published); not FDA approved","technology":"Poly-D,L-lactic acid (PDLLA) porous microspheres — biostimulator that triggers the body's own collagen production","measurement":"Vial (200 mg)","manufacturer":"REGEN Biotech, Inc. (Korea)","repeat_interval":"Sessions 4-6 weeks apart; maintenance every ~1-2 years","technical_specs":"200 mg lyophilised PDLLA per vial; IFU dilution 8 mL sterile water for face/shallow lines or 1.4 mL for deep wrinkles; full suspension can take 30+ min by hand-shaking.","before_treatment":"Avoid blood-thinning supplements and alcohol for a few days; avoid treatment right before events.","safety_suitability":"Avoid if pregnant/breastfeeding, with active infection or inflammation at the site, keloid tendency, uncontrolled autoimmune disease, or allergy to components. Nodules/granulomas are a known risk of poly-lactic acid products, especially with superficial or uneven injection; PDLLA cannot be dissolved like HA."},"recovery":{"flying":"Usually possible","makeup":"Next day","alcohol":"Avoid for 2-3 days","exercise":"Avoid strenuous exercise for 1-2 days","sauna_heat":"Avoid sauna/hot baths for about 1 week","back_to_daily":"Usually immediately","common_side_effects":["Small bumps at injection points (hours to ~1-2 days)","Redness","Swelling","Bruising","Tenderness"]},"quick_facts":{"pain":"Moderate","downtime":"1-3 days (swelling, small bumps, possible bruising)","results_last":"Around 2 years reported (individual variation)","treatment_time":"30-45 min (+ numbing; vial reconstitution beforehand)","results_visible":"Gradually over 1-3 months as collagen forms; initial fullness fades in days"},"alternatives":[{"name":"Juvelook Volume","catalog_id":"juvelook_volume","consider_when":"You want PDLLA plus HA for some immediate fullness."},{"name":"Sculptra","catalog_id":"sculptra","consider_when":"You prefer the original PLLA collagen stimulator with long clinical history."},{"name":"Hyaluronic Acid Filler","catalog_id":"hyaluronic_acid_filler","consider_when":"You need immediate, reversible volume."}],"before_after":[],"how_it_works":{"steps":[{"body":"The 200 mg PDLLA powder vial is mixed with sterile water (about 8 mL for face/fine lines, less for deep areas), often with lidocaine, and left to hydrate fully.","title":"Reconstitute"},{"body":"The area is disinfected and numbing cream applied.","title":"Cleanse & numb"},{"body":"Suspension is spread evenly under the skin with a cannula or needle in a fan or grid pattern.","title":"Inject"},{"body":"The area is massaged to distribute product; at-home massage may be advised for several days.","title":"Massage"}],"how_delivered":"Reconstituted PDLLA microparticle suspension injected into the deep dermis / subcutaneous layer","illustration_idea":"Porous PDLLA microspheres in the dermis with new collagen fibres forming around them over weeks.","what_touches_skin":"Cannula or fine needle + numbing cream","what_it_feels_like":"Pressure and stinging; moderate discomfort eased by lidocaine and numbing cream"}}}}